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Functional Lipid Nanosystems in Cancer
edited by Marlene Lucio, Carla M Lopes and Maria Elisabete Real Oliveira
- Format: eBook
- ISBN: 9781003056997
- Subject: General Biomedical Engineering
- Published: November 2021
For Course Instructors: Inspection Copies
Cancer remains one of the most challenging issues in modern medicine, being responsible for a high number of deaths every year. Recent important developments in cancer diagnosis and therapy based on the versatility of nanosystems have made it possible to incorporate multifunctional synergistic actions into a single delivery system.
This book compiles the research on the use of functional lipid nanosystems that combine different strategies in one single nanosystem to enhance overall cancer treatment. Besides providing an overview of the current functional nanosystem strategies, it also offers researchers essential theoretical background on cancer, the physiological barriers to its treatment, aspects related to the design and optimization of nanocarriers for cancer treatment, and clinical developments, including promises, safety issues, and the expected future. The editors bring together a group of scientists from all over the world to discuss the most relevant issues and to provide updates on functional lipid nanosystems and cancer.
Key Features:
- Covers research on lipid nanosystems for use in cancer therapy and diagnostics, including aspects from physiological barriers in cancer, strategies to overcome these barriers, classical therapeutic strategies, new therapeutic options, and hyphenated approaches for synergic treatments
- Includes contributions from experts in different topics such as cancer pathology and treatments, triggering strategies, targeting ligands, gene therapy
- Contains excellent figures illustrating research highlights taken from the latest and most interesting developments in the field of functional lipid nanosystems for cancer therapy
Chapter 1
Physiological Barriers in Cancer: A Challenge to Be Overcome
Livia P. Mendes, Can Sarisozen, and Vladimir P. Torchilin
Pages: 1-44
USD $34.95
Add to cartChapter 2
Cancer Chemotherapy, Bioactive Compounds, and Immunotherapy
Eva Fischer-Fodor, Alina Andreea Zimta, Mihail Buse, and Ioana Berindan Neagoe
Pages: 45-90
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Add to cartChapter 3
General Aspects of a Multifunctional Nanosystem
Marlene Lucio, Maria Elisabete C. D. Real Oliveira, and Carla M. Lopes
Pages: 91-188
USD $34.95
Add to cartChapter 4
Co-delivery of Anticancer Therapeutics via Lipid-Based Nanoscale Delivery Systems
Yao Fu
Pages: 189-230
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Add to cartChapter 5
Lipid-Based Nanocarriers for Co-delivery of Anticancer Drugs and Natural Compounds
Eduarda Fernandes, Telma Soares, Carla M. Lopes, Maria Elisabete C. D. Real Oliveira, and Marlene Lucio
Pages: 231-272
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Add to cartChapter 6
Co-delivery of Anticancer Drug and Adjuvant Agents
Luciana B. Lopes, Vanessa C. Dartora, Julia S. Passos, and Giovanna C. Salata
Pages: 273-306
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Add to cartChapter 7
Hybrid Nanosystems Composed by Lipid and Polymer Materials
Maria Mendes, Jessica Silva, Joao Basso, and Carla Vitorino
Pages: 307-350
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Add to cartChapter 8
Lipid Nanosystems: Targeted Nano-delivery of Therapeutic Agents in Treatment of Cancer
Azmat Ali Khan, Mumtaz Jabeen, Iftekhar Hassan, Mohammad Furqan, and Amer M. Alanazi
Pages: 351-378
USD $34.95
Add to cartChapter 9
Monoclonal Antibody Ligands for Liposomes Functionalization: Immunoliposomes Formulation and Clinical Status
Sara Zalba, Maria Merino, and Maria J. Garrido
Pages: 379-428
USD $34.95
Add to cartChapter 10
Active Targeting for Tumor Microenvironment: Integrin Binding Peptides
Mohammad Mashreghi and Mahmoud Reza Jaafari
Pages: 429-448
USD $34.95
Add to cartChapter 11
Targeting Liposomes to Metastatic Tumors with Antibodies Specific for VCAM-1
Melvin E. Klegerman
Pages: 449-470
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Add to cartChapter 12
Active Targeting: Mitochondria-Targeting Signal Peptides
Li Li
Pages: 471-484
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Add to cartChapter 13
Recent Developments of Light: Triggered Liposome Nanosystems for Cancer Treatments
Wenjie Chen, Wei Deng, and Ewa M. Goldys
Pages: 485-512
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Add to cartChapter 14
Ultrasound-Responsive Nanosystems
Kartick Chandra Majhi, Shrabani De, and Rashmi Madhuri
Pages: 513-554
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Add to cartChapter 15
Lipid-Based Nanosystems for Gene and Drug Co-delivery in Cancer Therapy
Christian Wolk and Richard D. Harvey
Pages: 555-596
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Add to cartChapter 16
The Therapeutical Window of Light: Modulating Receptor Proteins and Metabolic Pathways with Light and Its Importance for Disease Control
Odete Sofia Lopes Goncalves, Andreia C. Gomes, and Maria Teresa Neves-Petersen
Pages: 597-632
USD $34.95
Add to cartChapter 17
Magnetic Lipid-Based Nanosystems for Combined Therapy of Cancer
Ana Rita O. Rodrigues, Paulo J. G. Coutinho, and Elisabete M. S. Castanheira
Pages: 633-676
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Add to cartMarlene Lúcio obtained her PharmD (1999) and PhD in pharmaceutical chemistry (2006) from the Faculty of Pharmacy at the University of Porto, Portugal. In 2008, she received the European Young Chemist Award for her outstanding contribution to research in life sciences . Since then, she has been developing lipid-based nanosystems as membrane models to study the interactions between drugs and biointerfaces and as nanocarriers of bioactive compounds for several therapeutic applications. She is a researcher and invited professor at the University of Minho, Portugal.
Carla M. Lopes received her PharmD (2001) and PhD (2006) in pharmaceutical technology from the Faculty of Pharmacy at the University of Porto, Portugal. She is an assistant professor at Fernando Pessoa University. She has done scientific consulting for health companies and has more than 10 years of experience in the development of lipid-based nanocarriers for targeting the delivery of bioactive compounds. She is the author of several scientific articles published in international peer-reviewed journals.
Maria Elisabete C. D. Real Oliveira is associate professor with habilitation at the Physics Department of the University of Minho, Portugal. She obtained her BSc in physics from the University of Coimbra and her PhD from the University of Salford, UK, and the University of Minho. She was head of the master’s degree program in biophysics and bionanosystems from 2009 to 2014 and has been president of the Group of Colloids, Polymers and Interfaces of the Portuguese Chemical Society since 2013. Prof. Oliveira has over 10 years of experience in the development of liposomal nanosystems for biological applications, namely cancer cell transfection, and siRNA silencing therapy in cancer. She is the author of diverse scientific articles published in international peer-reviewed journals and 2 patents of a lipid drug delivery system. She was also the founder of the Spin-off Nanodelivery–I&D in Bionanotecnology, LDA.