The Tumor Stroma

Chapter 1

The Tumor Stroma: Key Component of Solid Tumors

Jai Pr akash

Pages: 1-16

Chapter 2

Cancer-Associated Fibroblasts: Building Blocks of the Tumor Stroma

Ahmed M. R. H. Mostafa, Alaa M. Ramadan, Arne Östman, and Jai Prakash

Pages: 17-54

Chapter 3

Tumor-Associated Macrophages: Biological Understanding and Therapeutic Opportunities

Siavash Mansouri and Rajkumar Savai

Pages: 55-92

Chapter 4

Biomarkers in the Tumor Stroma and Their Clinical Relevance

Barnali Deb, Rajan Datar, Sewanti Limaye, and Prashant Kumar

Pages: 93-122

Chapter 5

Physical Properties of the Tumor Stroma and Therapeutic Strategies

Zalak Bhut, Marcel Alexander Heinrich, and Jai Prakash

Pages: 123-166

Chapter 6

TGF-β Signalling in Cancer: Role and Therapeutic Targeting of the Tumour Stroma

Adilson Fonseca Teixeira, Peter ten Dijke, and Hong-Jian Zhu

Pages: 167-232

Chapter 7

Role of Integrins in the Tumor Stroma

Kunal Pednekar, Marcel Alexander Heinrich, and Jai Prakash

Pages: 233-286

Chapter 8

MicroRNA in the Tumor Stroma: Diagnostic and Therapeutic Implications

Tao Lu, Leon W. M. M. Terstappen, and Jai Prakash

Pages: 287-314

Chapter 9

Molecular Imaging of the Tumor Stroma and Beyond

F. A. Vuijk, R. Houvast, V. M. Baart, C. J. H. van de Velde, A. L. Vahrmeijer, D. E. Hilling, J. S. D. Mieog, M. Slingerland, L. F. de Geus-Oei, L. J. A. C. Hawinkels, and C. F. M Sier

Pages: 315-358

Chapter 10

3D in vitro Models to Mimic the Tumor Microenvironment

Marcel Alexander Heinrich, Ngoc Tien Huynh, Yu Shrike Zhang, and Jai Prakash

Pages: 359-412