A Systems Engineering Approach
Taking a unique, systems perspective, this book not only covers fundamental information on nanomedicine, but also provides an account of modeling, simulation, and experimental tools for dealing with challenges at the interface between nanotechnology and medicine. It is an excellent reference for researchers and students in this burgeoning field.Prof. Xiaobo Tan, Michigan State University, USA
- Format: Hardcover
- ISBN: 9789814241366
- Subject: Systems Design and Engineering
- Published: March 2009
- Pages: 348
This book offers a fundamental and comprehensive overview of nanomedicine from a systems engineering perspective, making it the first book in the field of quantitative nanomedicine based on systems theory. It will advance the knowledge of nanoscale science and engineering by efficiently employing quantitative tools for fundamental biomedical engineering and biological science research.
The book starts by introducing the concept of nanomedicine and provides basic mathematical modeling techniques that can be used to model nanoscale biomedical and biological systems. It then demonstrates how this idea can be used to model and analyze the central dogma of molecular biology, tumor growth and the immune system. Broad applications of the idea are further illustrated by Bayesian networks, multiscale and multiparadigm modeling and AFM engineering.
The book demonstrates how systems engineering, which has been very successful in conventional engineering, may help with nanomedicine.
• Nanomedicine — Dynamic Integration of Nanotechnology with Biomedical Science
• Fundamental Mathematical Modeling Techniques for Nano Biosystem
• A Mathematical Formulation of the Central Dogma of Molecular Biology
• Systems Approach to Characterize Living Drosophila Embryos for Biomedical Investigations
• Learning Signaling Pathway Structure
• Computational Modeling of Tumor Biobarriers: Implications for Delivery of Nano-based Therapeutics
• Multiscale-Multiparadigm Modeling and Simulation of Nanometer-Scale Systems and Processes for Nanomedical Applications
• Game Theoretical Formulation of the Immune System and Inspiration for Controlled Drug Delivery Application
Taking a unique, systems perspective, this book not only covers fundamental information on nanomedicine, but also provides an account of modeling, simulation, and experimental tools for dealing with challenges at the interface between nanotechnology and medicine. It is an excellent reference for researchers and students in this burgeoning field.~Prof. Xiaobo Tan, Michigan State University, USA
Nanomedicine blends science and engineering towards biomedical applications that range from medical use of nanomaterials to nanoelectronic biosensors. This interdisciplinary book addresses two main challenges which nanomedicine currently faces: quantitative description of drug effects at nanoscale and precise control of the drug effects.It contains eight chapters written by experts working in the field. One can find in this volume introduction to nanomedicine, description of basic mathematical techniques exploited in modeling of nano biosystems, a mathematical formulation of the central dogma of molecular biology, as well as a number of case studies. Namely, contributions to this volume deal with a system approach to characterization of living (Drosophila) embryos, learning signal pathway structures, computational modeling of tumor biobarriers, multiscale-multiparadigm modeling, simulations of nanomedical applications and a game theoretical formulation of the immune system for controlled drug delivery. The book illustrates the important role played by systems engineering in the development of nanomedicine and will be useful for graduate students and researchers working in this field.~Zentralblatt MATH