MicroRNA Profiling in Cancer

MicroRNA Profiling in Cancer

A Bioinformatics Perspective

by Yuriy Gusev

258 pages, 153.00 x 229.00 mm, 41 Color & 6 B/W

  • Hardcover
  • ISBN: 9789814267014
  • Published: October 2009

  • eBook - PDF
  • ISBN: 9789814267540

  • eBook - Kindle
  • ISBN: 9789814310390

  • eBook - EPUB
  • ISBN: 9789814310383

The recent discovery of microRNAs — a new class of non-coding RNAs — has revolutionized modern biomedical sciences. This book presents current advances in the emerging interdisciplinary field of microRNA research of human cancers from a unique perspective of quantitative sciences: bioinformatics, computational and systems biology and mathematical modeling.

This volume contains adaptations and critical reviews of the recent state-of-the-art studies, ranging from technological advances in microRNA detection and profiling, clinically oriented microRNA profiling in several human cancers, to a systems biology analysis of global patterns of microRNA regulation of signaling and metabolic pathways. Interactions with transcription factor regulatory networks and mathematical modeling of microRNA regulation are also discussed.