Aptamers

Chapter 1

History of Aptamer Development

Nasa Savory, Koichi Abe, Taiki Saito, and Kazunori Ikebukuro

Pages: 1

Chapter 2

Thioredoxin-Based Peptide Aptamers: Development and Applications

David S. Burz, Sergey Reverdatto, and Alexander Shekhtman

Pages: 27

Chapter 3

Aptamer Selection Methodologies

Penmetcha K. R. Kumar

Pages: 49

Chapter 4

Selection and Application of Catalytically Active Oligonucleotides

Rachel Gysbers, Kha Tram, Sepehr Manochehry, Dingran Chang, and Yingfu Li

Pages: 75

Chapter 5

Stem-Cell-Specific Aptamers for Targeted Cancer Therapy

Hadi Al. Shamaileh, Dongxi Xiang, Tao Wang, Wang Yin, Wei Duan, and Sarah Shigdar

Pages: 113

Chapter 6

Aptamers as Therapeutic Tools in Neurological Diseases

Lukas Aaldering, Shilpa Krishnan, Sue Fletcher, Stephen D. Wilton, and Rakesh N. Veedu

Pages: 151

Chapter 7

Aptamers in Bacterial, Viral, and Parasitic Diseases

Henning Ulrich, Arquimedes Cheffer, Flavia M. Zimbres, Attila Tarnok, and Carsten Wrenger

Pages: 169

Chapter 8

Aptamers as Tools for Targeted Drug Delivery

Anila Mathew and D. Sakthi Kumar

Pages: 187

Chapter 9

Aptamer–Liposome Conjugates: Current Art and Future Prospects

Oliver Ries and Stefan Vogel

Pages: 223

Chapter 10

Aptamers in Medical Diagnosis

Veli Cengiz Ozalp, Murat Kavruk, Ozlem Dilek, and Abdullah Tahir Bayrac

Pages: 253

Chapter 11

Molecular Imaging Utilizing Aptamer-Targeted Probes

Nicholas Fletcher and Kristofer Thurecht

Pages: 287

Chapter 12

First Therapeutic Aptamer: VEGF-Targeting Macugen

Marissa Leonard and Xiaoting Zhang

Pages: 319

Chapter 13

Aptamers: Scope, Limitations, and Future Prospects

John G. Bruno

Pages: 335