Poorly Soluble Drugs View Front MatterView Back Matter
Jenny Stanford Series on Pharmaceutical Analytics

Poorly Soluble Drugs

Dissolution and Drug Release

edited by Gregory K. Webster, J. Derek Jackson and Robert Bell

Even those who have been developing dissolution methods for years will find valuable information, since this text goes well beyond the basics of dissolution development for poorly soluble drugs. . . . The book walks through the lifecycle of a dissolution method for a poorly soluble compound, starting with solubility and intrinsic dissolution, including use of surfactants, has chapters that address several of the strategies used for formulation development and the staged approach to development of dissolution methods, provides chapters on alternatives to the traditional USP dissolution Apparatus 1 and 2, including Apparatus 3 and 4 and noncompendial approaches, then moves to some of the most interesting information describing biorelevant dissolution, clinically relevant dissolution, QbD approaches, and regulatory considerations. . . . Overall, this is a book that I strongly recommend for everyone involved in dissolution method development. It goes into much greater detail than similar texts and provides practical information that will prove helpful in addressing the concepts presented, both from a scientific and a regulatory perspective.

Gregory Martin, Dissolution Technologies
  • Format: Hardcover
  • ISBN: 9789814745451
  • Series: Jenny Stanford Series on Pharmaceutical Analytics
  • Subject: Analytical Chemistry
  • Published: December 2016
  • Pages: 703