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Drug Delivery with Targeted Nanoparticles

In Vitro and In Vivo Evaluation Methods

by Yılmaz Çapan, Adem Sahin and Hayrettin Tonbul

“Jenny Stanford continues its great job on providing first-class information on drug delivery and nanomedicine by publishing a new book, Drug Delivery with Targeted Nanoparticles: In Vitro and In Vivo Evaluation Methods, edited by Profs. Yılmaz Çapan, Adem Şahin, and Hayrettin Tonbul. Twenty-seven chapters in this book written by the leading scientists in the field cover multiple topics—from nanoparticle properties and characterization to regulatory issues, and from targeted nanoparticles to stimuli-sensitive ones. Very useful reading for many in the field.”

Prof. Vladimir Torchilin, Northeastern University, USA
  • Format: Hardcover
  • ISBN: 9789814877756
  • Subject: Nanomedicine
  • Published: November 2021
  • Pages: 790

Nanotechnology has the potential to change every part of our lives. Today, nanotechnology-based products are used in many areas, and one of the most important areas is drug delivery. Nanoparticulate drug delivery systems not only provide controlled delivery of drugs and improved drug solubility but also improve drug efficiency and reduce side effects via targeting mechanisms. However, compared with conventional drug delivery systems, few nanoparticle-based products are on the market and almost all are nontargeted or only passively targeted systems. In addition, obtaining targeted nanoparticle systems is quite complex and requires several evaluation mechanisms. This book discusses the production, characterization, regulation, and currently marketed targeted nanoparticle systems in a broad framework. It provides an overview of targeted nanoparticles’ (i) in vitro characterization, such as particle size, stability, ligand density, and type; (ii) in vivo behavior for different targeting areas, such as tumor, brain, and vagina; and (iii) current advances in this field, including clinical trials and regulation processes.