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Handbook of Clinical Nanomedicine
Nanoparticles, Imaging, Therapy, and Clinical Applications
edited by Raj Bawa, Israel Rubinstein and Gerald F. Audette
“Dr. Bawa and his team have meticulously gathered the distilled experience of world-class researchers, clinicians and business leaders addressing the most salient issues confronted in product concept development and translation. Knowledge is power, particularly in nanomedicine translation, and this handbook is an essential guide that illustrates and clarifies our way to commercial success.”
Gregory Lanza, MD, PhD, Washington University Medical School, USA
- Format: Hardcover
- ISBN: 9789814669207
- Series: Jenny Stanford Series on Nanomedicine
- Subject: Nanomedicine
- Published: February 2016
- Pages: 1708
USD $615.00
For Course Instructors: Inspection Copies
Retailers:
This handbook provides a comprehensive roadmap of basic research in nanomedicine as well as clinical applications. However, unlike other texts in nanomedicine, it not only highlights current advances in diagnostics and therapeutics but also explores related issues like nomenclature, historical developments, regulatory aspects, nanosimilars and 3D nanofabrication. While bridging the gap between basic biomedical research, engineering, medicine and law, the handbook provides a thorough understanding of nano’s potential to address (i) medical problems from both the patient and health provider’s perspective and (ii) current applications and their potential in a healthcare setting.
Key Features:
- Examines the entire "product wheel" from creation of nanomedical products to final market introduction in a stand-alone, easily accessible format
- Serves as an essential reference for the novice and expert alike in fields such as medicine, law, biotechnology, pharmaceutical sciences, engineering, policy, future studies, ethics, licensing, and toxicology
- Addresses critical topics such as personalized medicine, ethics, environmental health, nomenclature, nano-economics, business strategy, licensing, intellectual property, FDA law, EPA law, and governmental policy issues
Chapter 1
Science at the Nanoscale: Introduction and Historical Perspective
Chin Wee Shong, PhD, Sow Chorng Haur, PhD, and Andrew T. S. Wee, PhD
Pages: 1
USD $34.95
Add to cartChapter 2
Nanomedicine: Dynamic Integration of Nanotechnology with Biomedical Science
Ki-Bum Lee, PhD, Aniruddh Solanki, PhD, John Dongun Kim, PhD, and Jongjin Jung, PhD
Pages: 21
USD $34.95
Add to cartChapter 3
A Small Introduction to the World of Nanomedicine
Rutledge Ellis-Behnke, PhD
Pages: 61
USD $34.95
Add to cartChapter 4
Top Ten Recent Nanomedical Research Advances
Melanie Swan, MBA
Pages: 73
USD $34.95
Add to cartChapter 5
The Coming Era of Nanomedicine
Fritz Allhoff, JD, PhD
Pages: 103
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Add to cartChapter 6
What’s in a Name? Defining “Nano” in the Context of Drug Delivery
Raj Bawa, MS, PhD
Pages: 127
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Add to cartChapter 7
Properties of Nanoparticulate Materials
Takuya Tsuzuki, PhD
Pages: 171
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Add to cartChapter 8
Solid Drug Nanoparticles: Methods for Production and Pharmacokinetic Benefits
Andrew Owen, PhD, and Steve P. Rannard, DPhil
Pages: 211
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Add to cartChapter 9
Design and Development of Approved Nanopharmaceutical Products
Heidi M. Mansour, PhD, RPh, Chun-Woong Park, PhD, and Raj Bawa, MS, PhD
Pages: 233
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Add to cartChapter 10
Nanosizing Approaches in Drug Delivery
Sandip Chavhan, PhD, Kailash Petkar, PhD, and Krutika Sawant, PhD
Pages: 273
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Add to cartChapter 11
Multilayered Nanoparticles for Personalized Medicine: Translation into Clinical Markets
ania Movia, PhD, Craig Poland, PhD, Lang Tran, PhD, Yuri Volkov, PhD, and Adriele Prina-Mello, PhD
Pages: 299
USD $34.95
Add to cartChapter 12
Nanomaterials for Pharmaceutical Applications
Brigitta Loretz, PhD, Ratnesh Jain, PhD, Prajakta Dandekar, PhD, Carolin Thiele, PhD, Yamada Hiroe, PhD, Babak Mostaghaci, PhD, Lian Qiong, MSc, and Claus-Michael Lehr, PhD
Pages: 319
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Add to cartChapter 13
Polysaccharides as Nanomaterials for Therapeutics
Shoshy Mizrahy, MSc, and Dan Peer, PhD
Pages: 365
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Add to cartChapter 14
The Story of C60 Buckminsterfullerene
Harold W. Kroto, PhD
Pages: 409
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Add to cartChapter 15
Applications of Nanoparticles in Medical Imaging
Jason L. J. Dearling, PhD, and Alan B. Packard, PhD
Pages: 443
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Add to cartChapter 16
Nanoimaging for Nanomedicine
Yuri L. Lyubchenko, PhD, DSc, Yuliang Zhang, Alexey V. Krasnoslobodtsev, PhD, and Jean-Christophe Rochet, PhD
Pages: 465
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Add to cartChapter 17
Nanoparticles for Multi-Modality Diagnostic Imaging and Drug Delivery
Catherine M. Lockhart, PharmD, and Rodney J. Y. Ho, PhD
Pages: 493
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Add to cartChapter 18
Magnetic Nanoparticles for Magnetic Resonance Imaging: A Translational Push toward Theranostics
Ryan A. Ortega, Thomas E. Yankeelov, PhD, and Todd D. Giorgio, PhD
Pages: 521
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Add to cartChapter 19
First-in-Human Molecular Targeting and Cancer Imaging Using Ultrasmall Dual-Modality C Dots
Michelle S. Bradbury, MD, PhD, and Ulrich Wiesner, PhD
Pages: 549
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Add to cartChapter 20
Atomic Force Microscopy for Nanomedicine
Shivani Sharma, PhD, an d James K. Gimzewski, PhD
Pages: 567
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Add to cartChapter 21
Atomic Force Microscopy Imaging and Probing of Amyloid Nanoaggregates
Yuri L. Lyubchenko, PhD, DSc, and Luda S. Shlyakhtenko, PhD
Pages: 589
USD $34.95
Add to cartChapter 22
Image-Based High-Content Analysis, Stem Cells and Nanomedicines: A Novel Strategy for Drug Discovery
Leonardo J. Solmesky, PhD, Yonatan Adalist, MSc, and Miguel Weil, PhD
Pages: 617
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Add to cartChapter 23
Viral Nanoparticles: Tools for Materials Science and Biomedicine
Nicole F. Steinmetz, PhD, and Marianne Manchester, PhD
Pages: 641
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Add to cartChapter 24
Bacterial Secretion Systems: Nanomachines for Infection and Genetic Diversity
Agnesa Shala, PhD, Michele Ferraro, MSc, and Gerald F. Audette, PhD
Pages: 657
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Add to cartChapter 25
The Vascular Cartographic Scanning Nanodevice
Frank J. Boehm
Pages: 687
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Add to cartChapter 26
Advancements in Ophthalmic Glucose Nanosensors for Diabetes Management
Angelika Domschke, PhD
Pages: 707
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Add to cartChapter 27
Towards Nanodiagnostics for Bacterial Infections
Georgette B. Salieb-Beugelaar, PhD, and Patrick R. Hunziker, MD
Pages: 749
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Add to cartChapter 28
Copaxone® in the Era of Biosimilars and Nanosimilars
Jill B. Conner, MS, PhD, Raj Bawa, MS, PhD, J. Michael Nicholas, PhD, and Vera Weinstein, PhD
Pages: 783
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Add to cartChapter 29
Doxil®: The First FDA-Approved Nanodrug—From an Idea to a Product (January 2015 Update)
Yechezkel Barenholz, PhD
Pages: 827
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Add to cartChapter 30
Nanotechnology and the Skin Barrier: Topical and Transdermal Nanocarrier-Based Delivery
Hagar I. Labouta, PhD, and Marc Schneider, PhD
Pages: 907
USD $34.95
Add to cartChapter 31
Application of Nanotechnology in Non-Invasive Topical Gene Therapy
Mahmoud Elsabahy, PhD, Maria Jimena Loureiro, MSc, and Marianna Foldvari, PhD, DPharmSci
Pages: 937
USD $34.95
Add to cartChapter 32
Nanocarriers in the Therapy of Inflammatory Disease
Alf Lamprecht, PhD
Pages: 973
USD $34.95
Add to cartChapter 33
Advanced 3D Nano/Microfabrication Techniques for Tissue and Organ Regeneration
Benjamin Holmes, MSc, Thomas J. Webster, PhD, and Lijie Grace Zhang, PhD
Pages: 989
USD $34.95
Add to cartChapter 34
Nanomedicine for Acute Lung Injury/Acute Respiratory Distress Syndrome: A Shifting Paradigm?
Ruxana T. Sadikot, MD, and Israel Rubinstein, MD
Pages: 1027
USD $34.95
Add to cartChapter 35
Nanoviricides: Targeted Anti-Viral Nanomaterials
Randall W. Barton, PhD, Jayant G. Tatake, PhD, and Anil R. Diwan, PhD
Pages: 1039
USD $34.95
Add to cartChapter 36
Nanotechnology in Tissue Engineering for Orthopaedics
Lesley M. Hamming, PhD, JD, and Mark G. Hamming, MD
Pages: 1053
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Add to cartChapter 37
Applications of Nanomaterials in Dentistry
Karolina Jurczyk, DDS, PhD, and Mieczyslaw Jurczyk, PhD, DSc
Pages: 1073
USD $34.95
Add to cartChapter 38
Biomimetic Applications in Regenerative Medicine: Scaffolds, Transplantation Modules, Tissue Homing Devices, and Stem Cells
David W. Green, PhD, and Besim Ben-Nissan, PhD
Pages: 1109
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Add to cartChapter 39
Potential Applications of Nanotechnology in the Nutraceutical Sector
Shu Wang, MD, PhD, and Jia Zhang, MS
Pages: 1141
USD $34.95
Add to cartChapter 40
Designing Nanocarriers for the Effective Treatment of Cardiovascular Diseases
Bhuvaneshwar Vaidya, MPharm, PhD, and Suresh P. Vyas, MPharm, PhD
Pages: 1167
USD $34.95
Add to cartChapter 41
Carbon Nanotubes as Substrates for Neuronal Growth
Cécilia Ménard-Moyon, PhD
Pages: 1197
USD $34.95
Add to cartChapter 42
Polymeric Nanoparticles for Cancer Therapeutics
Mohit S. Verma, Joshua E. Rosen, Ameena Meerasa, Serge Yoffe, MEng, and Frank X. Gu, PhD
Pages: 1239
USD $34.95
Add to cartChapter 43
Nanotechnology for Radiation Oncology
Srinivas Sridhar, PhD, Ross Berbeco, PhD, Robert A. Cormack, PhD, and G. M. Makrigiorgos, PhD
Pages: 1273
USD $34.95
Add to cartChapter 44
Gold Nanoparticles against Cancer
Joan Comenge, PhD, Francisco Romero, PhD, Aurora Conill, MS, and Víctor F. Puntes, PhD
Pages: 1293
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Add to cartChapter 45
Solid Lipid Nanoparticles and Nanostructured Lipid Carriers for Cancer Therapy
Melike Üner, PhD
Pages: 1315
USD $34.95
Add to cartChapter 46
Nanomedicines Targeted to Aberrant Cancer Signaling and Epigenetics
Archana Retnakumari, MTech, Parwathy Chandran, MTech, Ranjith Ramachandran, MSc, Giridharan L. Malarvizhi, MTech, Shantikumar Nair, PhD, and Manzoor Koyakutty, PhD
Pages: 1347
USD $34.95
Add to cartChapter 47
Biodegradable Nanoparticle-Based Antiretroviral Therapy across the Blood-Brain Barrier
Supriya D. Mahajan, PhD, Yun Yu, PhD, Ravikumar Aalinkeel, PhD, Jessica L. Reynolds, PhD, Bindukumar B. Nair, PhD, Manoj J. Mammen, MD, Tracey A. Ignatowski, PhD, Chong Cheng, PhD, and Stanley A. Schwartz, PhD, MD
Pages: 1379
USD $34.95
Add to cartChapter 48
HIV-Specific Immunotherapy with Synthetic Pathogen-Like Nanoparticles
Orsolya Lorincz, PhD, and Julianna Lisziewicz, PhD
Pages: 1407
USD $34.95
Add to cartChapter 49
Biomedical Engineering and Nanoneurosurgery: From the Laboratory to the Operating Room
Mario Ganau, MD, PhD, Roberto I. Foroni, PhD, Andrea Soddu, PhD, and Rossano Ambu, MD
Pages: 1433
USD $34.95
Add to cartChapter 50
Nanotechnology-Based Systems for Microbicide Development
Rute Nunes, Carole Sousa, Bruno Sarmento, PhD, and José das Neves, PhD
Pages: 1445
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Add to cartChapter 51
Nanotechnology-Based Solutions to Combat the Emerging Threat of Superbugs: Current Scenario and Future Prospects
Nisha C. Kalarickal, PhD, and Yashwant R. Mahajan, PhD
Pages: 1493
USD $34.95
Add to cartChapter 52
Nanolithography and Biochips’ Role in Viral Detection
Inbal Tsarfati-BarAd and Levi A. Gheber, PhD
Pages: 1517
USD $34.95
Add to cartChapter 53
Lectins as Nano-Tools in Drug Delivery
Anita Gupta, MSc, PhD, and G. S. Gupta, MSc, PhD
Pages: 1529
USD $34.95
Add to cartChapter 54
Diagnostics of Ebola Hemorrhagic Fever Virus
Ariel Sobarzo, PhD, Robert S. Marks, PhD, and Leslie Lobel, MD, PhD
Pages: 1577
USD $34.95
Add to cartChapter 55
Nanomedicine as a Strategy to Fight Thrombotic Diseases
Mariana Varna, PhD, Maya Juenet, MSc, Richard Bayles, PhD, Mikael Mazighi, MD, PhD, Cédric Chauvierre, PhD, and Didier Letourneur, PhD
Pages: 1611
USD $34.95
Add to cartRaj Bawa, PhD, MD, is president of Bawa Biotech LLC (founded 2002), a biotech/pharma consultancy and patent law firm based in Ashburn, Virginia. Trained as a microbiologist and biochemist, he is an inventor, author, entrepreneur, professor, and registered patent agent (since 2002) licensed to practice before the US Patent & Trademark Office. He is currently scientific advisor to Teva Pharmaceutical Industries, Israel (since 2010); visiting research scholar at Pharmaceutical Research Institute of Albany Pharmacy, Albany, New York; and full professor (adjunct) at NOVA in Annandale, Virginia (since 2004). He is VP/chief IP officer at Guanine, Inc., in Rensselaer, New York (since 2017), a company focused on rapid, accurate detection of infective pathogens. Dr. Bawa has served as a principal investigator of various NCI research grants, and most recently as a principal investigator of a CDC grant to develop an assay for carbapenemase resistant bacteria. Previously, he was an adjunct professor at Rensselaer Polytechnic Institute, Troy, New York, from 1998 to 2018. He held various positions at the US Patent Office, including primary examiner from 1996 to 2002. He earned a BSc (Honors School) in microbiology, MS in cancer biology, PhD in biophysics/biochemistry, and MD. Currently, he is a life member of Sigma Xi, cochair of the nanotech and precision medicine committees of the American Bar Association and founding director of the American Society for Nanomedicine (established 2008). He has authored over 100 publications, edited 10 texts, and serves on the editorial boards of numerous peer-reviewed journals, including serving as an associate editor of Nanomedicine (Elsevier).
Gerald F. Audette, PhD, has been a faculty member at York University in Toronto, Canada, in the Department of Chemistry since 2006. Currently he is associate professor in the department and a member of the Centre for Research on Biomolecular Interactions at York University. Dr. Audette is the co-editor of volumes 1-4 of the Pan Stanford Series on Nanomedicine and is a subject editor of structural chemistry and crystallography for the journal FACETS.
“Dr. Bawa and his team have meticulously gathered the distilled experience of world-class researchers, clinicians and business leaders addressing the most salient issues confronted in product concept development and translation. Knowledge is power, particularly in nanomedicine translation, and this handbook is an essential guide that illustrates and clarifies our way to commercial success.”
~Gregory Lanza, MD, PhD, Washington University Medical School, USA
“This is an outstanding, comprehensive volume that crosscuts disciplines and topics fitting individuals from a variety of fields looking to become knowledgeable in medical nanotech research and its translation from the bench to the bedside.”
~Shaker A. Mousa, PhD, MBA, Albany College of Pharmacy and Health Sciences, USA
“Masterful! This handbook will have a welcome place in the hands of students, educators, clinicians and experienced scientists alike. In a rapidly evolving arena, the authors have harnessed the field and its future by highlighting both current and future needs in diagnosis and therapies. Bravo!”
~Howard E. Gendelman, MD, University of Nebraska Medical Center, USA
“It is refreshing to see a handbook that does not merely focus on preclinical aspects or exaggerated projections of nanomedicine. Unlike other books, this handbook not only highlights current advances in diagnostics and therapies but also addresses critical issues like terminology, regulatory aspects and personalized medicine.”
~Gert Storm, PhD, Utrecht University, The Netherlands