Glycomics (a comprehensive study of glycans, often denoted as the third alphabet of molecular biology, besides nucleic acids and proteins) relies the techniques that use heavy machinery, such as mass spectrometry, liquid chromatography, and capillary electrophoresis. The use of biosensors and biochips for glycan analysis offers the possibility of lower costs, lower time and sample consumption, and ease of use. This highly interdisciplinary book introduces students, researchers, and beginning professors to the broad scope of this area, including the basics of nanotechnology and materials science, glycomics, and bioanalytical chemistry, as well as several historical facts and contexts and future perspectives. The introductory chapters are utilized in the book later for the state-of-the-art chapters on glycan-based diagnostics and imaging, enrichment techniques, and therapy, which makes this book unique and of great interest to a wide audience. The authors are skilled specialists and research scientists with many years of experience in this area and former investigators on a prestigious European Research Council Starting Grant.
- The only book to provide an introduction to the field
- Interdisciplinary in nature and hence of interest to a broad readership
- Covers the most recent research in the area of glycomics
This book will be of particular interest to students with basic knowledge in analytical chemistry, starting researchers in nanotechnology- and biomedicine-oriented research; university teachers and professionals in the field of chemistry, biology, medicine, material engineering and nanotechnology; wider audience interested in omics research, more specifically in proteomics and glycoproteomics for medical diagnostics and therapy
“This book brings a new and useful perspective on the development of diagnostic and therapeutic tools based on carbohydrates. It covers an impressive range of disciplines from introductions to nanotechnology and glycan biology, through the intricacies of assay development and finally future applications of the technologies presented. The breadth of topics is such that even an expert in one aspect of the field will find new insights in the many complementary chapters.”~Prof. Bruce Turnbull, University of Leeds, UK
“This excellent book provides a wide range of readers with the emerging aspects of glycoscience and nanotechnology, whose origins are quite different and thus few seem to understand both. However, their fusion will generate many new ideas to innovate not only materials/polymer sciences (e.g., cellulose/chitin nanofibers and cyclodextrin-rotaxanes) but also life sciences concerning immunology, biologics, oncology, regenerative medicine, infection, and analytical sciences. The book will contribute to increasing the chance of serendipity as well as to the Sustainable Development Goals on this planet.”~Prof. Jun Hirabayashi, National Institute of Advanced Industrial Science and Technology, Japan