The past two decades have seen rapid development of micro-/nanotechnologies with the integration of chemical engineering, biomedical engineering, chemistry, and life sciences to form bio-microelectromechanical systems (bio-MEMS) or lab-on-chip devices, which help perform cellular analysis in a complex micro-/nanoflluidic environment with minimum sample consumption and have potential biomedical applications.
To date, few books are published in this field and researchers are unable to find specialized content. This book compiles cutting-edge research on cell manipulation, separation, and analysis using microfluidics and bio-MEMS. It illustrates the use of micro-robots for biomedical applications, vascularized microfluidic organs-on-a-chip and their applications, as well as DNA gene microarray biochips and their applications. It also elaborates on neuronal cell activity in microfluidic compartments, microvasculature and microarray gene patterning, different physical methods for drug delivery and analysis, micro-/nanoparticle preparation and separation in a micro-/nanofluidic environment, and the potential biomedical applications of micro-/nanoparticles. This book can be used by academic researchers, especially those involved in biomicrofluidics and bio-MEMS, and undergraduate- and graduate-level students of bio-MEMS/bio-NEMS, biomicrofluidics, biomicrofabricatios, micro-/nanofluidics, biophysics, single-cell analysis, bionanotechnology, drug delivery systems, and biomedical microdevices. Readers can gain knowledge of different aspects of microfluidics and bio-MEMS devices; their design, fabrication, and packaging; and biomedical applications. The book will also help biotechnology-based industries, where research and development is on-going in cell-based analysis, diagnosis, and drug screening.
- Covers wide research on microfluidic and bio-MEMS device-based cell manipulation, separation, and analysis
- Illustrates vascularized microfluidic organs-on-a-chip, microarray gene patterning, particle mixing and separation, and neuronal cell activity in a microfluidic environment
- Covers different physical methods for drug delivery and therapeutics and diagnostics applications
- Includes a contribution from Prof. Fan-Gang Tseng, an ASME fellow, general co-chair of Micro-TAS 2018, and board member of the Taiwan Nanoengineering and Microsystem Technology Association
- Is illustrated throughout with excellent figures and references to accompany each section
“Due to the multidisciplinary nature of microfluidics and bio-microelectromechanical systems (bio-MEMS), it is challenging to handle this topic. Instead of trying to fully cover the field of microfluidics, this book focuses on several interesting directions with in-depth analysis and discussion. I strongly recommend this book for graduate-level courses where students with a preliminary background of bio-MEMS can utilize it to conduct case studies to deepen their understanding and enrich their experience of microfluidics.”~Prof. Jian Chen
“Dr. Santra’s book on microfluidics and bio-MEMS gives a basic introduction to bio-MEMS and covers a wide range of applications. It is illustrated with over 180 figures and describes key concepts intuitively. Major studies published in the 2010s can be grasped concisely.”~Prof. Moeto Nagai